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KIF20B Antibody

  • 货号：
    CSB-PA080032
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96Q89
  • 基因名：
    KIF20B
  • 别名：
    Cancer/testis antigen 90 antibody; CT90 antibody; KI20B_HUMAN antibody; KIF20B antibody; Kinesin-like protein KIF20B antibody; Kinesin-related motor interacting with PIN1 antibody; KRMP1 antibody; M-phase phosphoprotein 1 antibody; MPHOSPH1 antibody; MPP 1 antibody; Mpp1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human MPP1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.
  • 基因功能参考文献：
    1. MPP1 is a new mitotic molecular motor required for completion of cytokinesis PMID: 12740395
  • 亚细胞定位：
    Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cell projection, axon. Cell projection, growth cone.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 组织特异性：
    Brain, ovary, kidney and testis (at protein level). Overexpressed in bladder cancer cells (at protein level). Expressed in testis. Overexpressed in bladder cancer cells.
  • 数据库链接：

    HGNC: 7212

    OMIM: 605498

    KEGG: hsa:9585

    STRING: 9606.ENSP00000260753

    UniGene: Hs.240