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KIAA0319L Antibody

  • 货号：
    CSB-PA816919LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA816919LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA816919LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KIAA0319L Polyclonal antibody
  • Uniprot No.：
    Q8IZA0
  • 基因名：
    KIAA0319L
  • 别名：
    Dyslexia-associated protein KIAA0319-like protein antibody; K319L_HUMAN antibody; KIAA0319 like antibody; KIAA0319L antibody; KIAA1837 antibody; PKD1 like antibody; Polycystic kidney disease 1 like antibody; Polycystic kidney disease 1 related antibody; PP791 antibody; RP4 765A10.3 antibody; Uncharacterized protein KIAA0319 like antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Dyslexia-associated protein KIAA0319-like protein (479-718AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KIAA0319L Antibody (CSB-PA816919LA01HU)，的标记方式是Non-conjugated。对于KIAA0319L Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA816919LB01HU KIAA0319L Antibody, HRP conjugated ELISA
    FITC CSB-PA816919LC01HU KIAA0319L Antibody, FITC conjugated
    Biotin CSB-PA816919LD01HU KIAA0319L Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Possible role in axon guidance through interaction with RTN4R.; (Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system.
  • 基因功能参考文献：
    1. Optic nerve damage may change retinal architecture to allow greater penetration of an AAV2 virus to transduce several additional cell types in the inner nuclear layer. PMID: 29204649
    2. AAVR directly binds to AAV2 particles, and that anti-AAVR antibodies efficiently block AAV2 infection; moreover, genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection PMID: 26814968
    3. Results identify KIAA0319L as novel susceptibility loci for Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). KIAA0319L was overexpressed in peripheral blood cells of SSc and SLE patients compared with healthy controls. PMID: 23740937
    4. KIAA0319L remains an intriguing positional and functional candidate for RD, especially when considered alongside the supporting evidence for its homolog KIAA0319 on chromosome 6p. PMID: 19085271
  • 亚细胞定位：
    Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 组织特异性：
    Expressed in cortical neurons in the brain cortex (at protein level).
  • 数据库链接：

    HGNC: 30071

    OMIM: 613535

    KEGG: hsa:79932

    STRING: 9606.ENSP00000318406

    UniGene: Hs.456507