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KIAA0100 Antibody

  • 货号：
    CSB-PA080052
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q14667
  • 基因名：
    KIAA0100
  • 别名：
    Antigen MLAA-22 antibody; BCOX antibody; BCOX1 antibody; Breast cancer-overexpressed gene 1 protein antibody; CT101 antibody; DKFZp686M0843 antibody; K0100_HUMAN antibody; KIAA0100 antibody; MGC111488 antibody; MGC134981 antibody; UPF0378 protein KIAA0100 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human KIAA0100.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in membrane trafficking.
  • 基因功能参考文献：
    1. loss of miR-195 expression and thus uncontrolled BCOX1 upregulation might drive prostate cancer metastasis. PMID: 26338045
    2. High BCOX1 expression may serve as a novel marker of poor prognosis and a potential therapeutic target for patients with invasive ductal carcinomas of the breast. PMID: 24489812
    3. MLAA-22 is a novel acute monocytic leukemia-associated antigen gene located on chromosome 17q11.2. PMID: 18549609
    4. BCOX1 mRNA signal is mainly located in the cytoplasm of breast carcinoma epithelial cells. mRNA expression was moderately elevated in ductal in situ carcinoma, peaked in invasive breast carcinoma and metastatic breast carcinoma cells (MET) (BCOX1) PMID: 16289875
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    SABRE family
  • 组织特异性：
    Expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells, ductal in situ carcinoma (DCIS), invasive breast carcinoma (IBC) and metastatic breast carcinoma cells (MET).
  • 数据库链接：

    HGNC: 28960

    OMIM: 610664

    KEGG: hsa:9703

    UniGene: Hs.151761