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KCNG3 Antibody

  • 货号：
    CSB-PA703878
  • 规格：
    ￥880
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
    • Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
  • 其他：

产品详情

  • Uniprot No.：
    Q8TAE7
  • 基因名：
    KCNG3
  • 别名：
    KCNG3; Potassium voltage-gated channel subfamily G member 3; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic Peptide
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC,ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC IHC-p:1:100-200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1.
  • 基因功能参考文献：
    1. the correlation between dismal prognosis and Kv10.1 expression to patients with brain metastases or glioblastoma multiforme and, moreover, they strongly suggest a role of tricyclic antidepressants for personalized therapy of brain malignancies. PMID: 26530050
    2. [review] an overview of the current status of data linking K(V)10.1 to cancer, and techniques that could exploit K(V)10.1's properties for the management of cancer PMID: 22204340
    3. These results indicate that Kv6.3 is a novel member of the voltage-gated K(+) channel which functions as a modulatory subunit of the Kv2.1 channel. PMID: 11852086
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族：
    Potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.3/KCNG3 sub-subfamily
  • 组织特异性：
    Expressed in the brain, liver, testis, small intestine, colon, thymus and adrenal gland.
  • 数据库链接：

    HGNC: 18306

    OMIM: 606767

    KEGG: hsa:170850

    STRING: 9606.ENSP00000304127

    UniGene: Hs.352633