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IRAK1BP1 Antibody

  • 货号：
    CSB-PA048353
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human fetal liver tissue, mouse heart tissue, human testis tissue, Primary antibody: CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/475, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

产品详情

  • Uniprot No.：
    Q5VVH5
  • 基因名：
    IRAK1BP1
  • 别名：
    ActA binding protein 3 antibody; AIP70 antibody; IKBP1_HUMAN antibody; Interleukin 1 receptor associated kinase 1 binding protein 1 antibody; Interleukin-1 receptor-associated kinase 1-binding protein 1 antibody; IRAK1-binding protein 1 antibody; IRAK1BP1 antibody; Signaling molecule that associates with Pelle-like kinase antibody; SIMPL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human IRAK1BP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity.
  • 基因功能参考文献：
    1. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 coactivator function of SIMPL. PMID: 17079333
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    IRAK1BP1 family
  • 数据库链接：

    HGNC: 17368

    OMIM: 615375

    KEGG: hsa:134728

    STRING: 9606.ENSP00000358956

    UniGene: Hs.656212