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IQCG Antibody

  • 货号：
    CSB-PA867116LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse heart tissue, Mouse skeletal muscle tissue
      All lanes: IQCG antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 41 kDa
      Observed band size: 52, 4 kDa
    • Immunofluorescent analysis of HepG2 cells using CSB-PA867116LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IQCG Polyclonal antibody
  • Uniprot No.：
    Q9H095
  • 基因名：
    IQCG
  • 别名：
    IQCG antibody; DRC9Dynein regulatory complex protein 9 antibody; IQ domain-containing protein G antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human IQ domain-containing protein G protein (1-134AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，IQCG Antibody (CSB-PA867116LA01HU)，的标记方式是Non-conjugated。对于IQCG Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA867116LB01HU IQCG Antibody, HRP conjugated ELISA
    FITC CSB-PA867116LC01HU IQCG Antibody, FITC conjugated
    Biotin CSB-PA867116LD01HU IQCG Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
  • 基因功能参考文献：
    1. human NUP98-IQCG fusion protein could induce fatal and transplantable acute myelomonocytic leukemia in a mouse model PMID: 26675333
  • 亚细胞定位：
    Cytoplasm. Cell projection, cilium, flagellum. Cell projection, cilium. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme.
  • 蛋白家族：
    DRC9 family
  • 数据库链接：

    HGNC: 25251

    OMIM: 612477

    KEGG: hsa:84223

    STRING: 9606.ENSP00000265239

    UniGene: Hs.591675