Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. IP6K1 Antibody

IP6K1 Antibody

  • 货号：
    CSB-PA011770LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: IP6K1 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 51, 32 kDa
      Observed band size: 51 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IP6K1 Polyclonal antibody
  • Uniprot No.：
    Q92551
  • 基因名：
  • 别名：
    ATP:1D myo inositol hexakisphosphate phosphotransferase antibody; IHPK1 antibody; Inositol hexakisphosphate kinase 1 antibody; Inositol hexaphosphate kinase 1 antibody; InsP6 antibody; InsP6 kinase 1 antibody; Ip6k1 antibody; IP6K1_HUMAN antibody; Itpk6 antibody; Pi uptake stimulator antibody; PiUS antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Inositol hexakisphosphate kinase 1 protein (1-441AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，IP6K1 Antibody (CSB-PA011770LA01HU)，的标记方式是Non-conjugated。对于IP6K1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA011770LB01HU IP6K1 Antibody, HRP conjugated ELISA
    FITC CSB-PA011770LC01HU IP6K1 Antibody, FITC conjugated
    Biotin CSB-PA011770LD01HU IP6K1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
  • 基因功能参考文献：
    1. IP6K1 physiologically regulates neuronal migration by binding to alpha-actinin and influencing phosphorylation of both FAK and alpha-actinin through its product 5-diphosphoinositol pentakisphosphate. PMID: 28154132
    2. provides the first evidence for the involvement of IP6Ks in dynein function and proposes that inositol pyrophosphate-mediated pyrophosphorylation may act as a regulatory signal to enhance dynein-driven transport PMID: 27474409
    3. IP6K1 is also involved in early cytoskeleton remodeling events during cancer progression. PMID: 27140681
    4. IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4-CSN complex, thereby regulating nucleotide excision repair and cell death. PMID: 25349427
    5. we identified IP6Ks as novel nuclear and cytosolic InsP6- (and InsP5-) dephosphorylating enzymes whose activity is sensitively driven by a decrease in the cellular ATP/ADP ratio PMID: 24865181
    6. FGF2-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 and osteoblast gene expression. PMID: 23322705
    7. IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus PMID: 15221640
    8. Results report the characterization of an inhibitor, N(2)-(m-(trifluoromethy)lbenzyl) N(6)-(p-nitrobenzyl)purine (TNP), selective for inositol hexakisphosphate kinases. PMID: 19208622

    显示更多

    收起更多

  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Inositol phosphokinase (IPK) family
  • 数据库链接：

    HGNC: 18360

    OMIM: 606991

    KEGG: hsa:9807

    STRING: 9606.ENSP00000323780

    UniGene: Hs.386168