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INTS10 Antibody

  • 中文名称：
    INTS10兔多克隆抗体
  • 货号：
    CSB-PA011758GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NVR2
  • 基因名：
    INTS10
  • 别名：
    INTS10 antibody; C8orf35 antibody; Integrator complex subunit 10 antibody; Int10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human INTS10
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.
  • 基因功能参考文献：
    1. Genome-wide association study in Chinise population highlights a novel antiviral gene INTS10 at 8p21.3 in the clearance of HBV infection. INST10 suppresses HBV replication via IRF3 in liver cells. PMID: 27244555
    2. Using a 7,781-sample pan-cancer dataset, we first confirmed this in POLR2A are known to confer elevated sensitivity to pharmacological suppression.hese include the POLR2A interacting protein INTS10 as well as genes involved in mRNA splicing, nonsense-mediated mRNA PMID: 28027311
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Integrator subunit 10 family
  • 数据库链接：

    HGNC: 25548

    OMIM: 611353

    KEGG: hsa:55174

    STRING: 9606.ENSP00000381064

    UniGene: Hs.512627