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INMT Antibody

  • 货号：
    CSB-PA011723GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O95050
  • 基因名：
    INMT
  • 别名：
    Amine N methyltransferase antibody; Amine N-methyltransferase antibody; Aromatic alkylamine N methyltransferase antibody; Aromatic alkylamine N-methyltransferase antibody; Arylamine N methyltransferase antibody; Arylamine N-methyltransferase antibody; Indolamine N-methyltransferase antibody; Indolethylamine N methyltransferase antibody; Indolethylamine N-methyltransferase antibody; Inmt antibody; INMT_HUMAN antibody; nicotine N methyltransferase antibody; TEMT antibody; thioester S methyltransferase like antibody; Thioether S methyltransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human INMT
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds.
  • 基因功能参考文献：
    1. study suggests that rs77743549 of INMT may be associated with the risk for Hirschsprung's disease PMID: 26183064
    2. genome-wide association studies in populations in Argentina/Bangladeshi: Three SNPs in INMT (rs6970396, rs1061644, rs4270015) are associated with production of trimethylselenonium (TMSe); urinary Se excretion is up-regulated in TMSe-producing women. PMID: 26537946
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family
  • 组织特异性：
    Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult a
  • 数据库链接：

    HGNC: 6069

    OMIM: 604854

    KEGG: hsa:11185

    UniGene: Hs.632629