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IMPG2 Antibody

  • 货号：
    CSB-PA011704LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of Hela cells with CSB-PA011704LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IMPG2 Polyclonal antibody
  • Uniprot No.：
    Q9BZV3
  • 基因名：
    IMPG2
  • 别名：
    IMPG2 antibody; IPM200 antibody; Interphotoreceptor matrix proteoglycan 2 antibody; Interphotoreceptor matrix proteoglycan of 200 kDa antibody; IPM 200 antibody; Sialoprotein associated with cones and rods proteoglycan antibody; Spacrcan antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Interphotoreceptor matrix proteoglycan 2 protein (616-759AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，IMPG2 Antibody (CSB-PA011704LA01HU)，的标记方式是Non-conjugated。对于IMPG2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA011704LB01HU IMPG2 Antibody, HRP conjugated ELISA
    FITC CSB-PA011704LC01HU IMPG2 Antibody, FITC conjugated
    Biotin CSB-PA011704LD01HU IMPG2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.
  • 基因功能参考文献：
    1. IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families. PMID: 25085631
    2. Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life. PMID: 24876279
    3. identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa PMID: 20673862
    4. IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival PMID: 10542133
  • 相关疾病：
    Retinitis pigmentosa 56 (RP56); Macular dystrophy, vitelliform, 5 (VMD5)
  • 亚细胞定位：
    Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
  • 组织特异性：
    Expressed in the retina (at protein level). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and t
  • 数据库链接：

    HGNC: 18362

    OMIM: 607056

    KEGG: hsa:50939

    STRING: 9606.ENSP00000193391

    UniGene: Hs.209249