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IL17RE Antibody

  • 货号：
    CSB-PA011606GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8NFR9
  • 基因名：
  • 别名：
    IL17RE antibody; UNQ3056/PRO9877 antibody; Interleukin-17 receptor E antibody; IL-17 receptor E antibody; IL-17RE antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human IL17RE
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
  • 基因功能参考文献：
    1. IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens. PMID: 21993849
  • 亚细胞定位：
    [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Secreted.
  • 组织特异性：
    Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
  • 数据库链接：

    HGNC: 18439

    OMIM: 614995

    KEGG: hsa:132014

    STRING: 9606.ENSP00000295980

    UniGene: Hs.390823