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IL12B Antibody

  • 货号：
    CSB-PA011587YA01SH
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Interleukin-12 subunit beta antibody at 14μg/ml + K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 37 kDa
      Observed band size: 37 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011587YA01SH at dilution of 1:10
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA011587YA01SH at dilution of 1:10
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Sheep IL12B Polyclonal antibody
  • Uniprot No.：
    P68220
  • 基因名：
  • 别名：
    IL12B antibody; Interleukin-12 subunit beta antibody; IL-12B antibody; Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody; CLMF p40 antibody; IL-12 subunit p40 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Sheep
  • 免疫原：
    Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA)
  • 免疫原种属：
    Sheep
  • 标记方式：
    Non-conjugated

    本页面中的产品，IL12B Antibody (CSB-PA011587YA01SH)，的标记方式是Non-conjugated。对于IL12B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA011587YB01SH IL12B Antibody, HRP conjugated ELISA
    FITC CSB-PA011587YC01SH IL12B Antibody, FITC conjugated
    Biotin CSB-PA011587YD01SH IL12B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
  • 基因功能参考文献：
    1. The aim of the study was to assess the prognostic significance of Tumor Necrosis Factor-alpha, Interleukin-12(p40), Interleukin-6 and Interleukin 10 levels in cerebrospinal fluid (CSF) in sheep with encephalitic listeriosis. PMID: 25817420
    2. Local intraocular production of IL-12 p40 (but not IL-4) prolongs corneal graft survival significantly PMID: 16081789
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Type I cytokine receptor family, Type 3 subfamily
  • 数据库链接：

    KEGG: oas:443472

    UniGene: Oar.721