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IARS2 Antibody

  • 货号：
    CSB-PA229275
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from RAW264.7 cells and COS-7 cells, using IARS2 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IARS2 antibody.
    • Immunofluorescence analysis of HepG2 cells, using IARS2 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IARS2 Polyclonal antibody
  • Uniprot No.：
    Q9NSE4
  • 基因名：
    IARS2
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human IARS2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
    2. Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
    3. The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
    4. This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867
  • 相关疾病：
    Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 数据库链接：

    HGNC: 29685

    OMIM: 612801

    KEGG: hsa:55699

    STRING: 9606.ENSP00000303279

    UniGene: Hs.262823