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HSPA12A Antibody

  • 货号：
    CSB-PA010817LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate, 293 whole cell lysate, HepG2 whole cell lysate
      All lanes: HSPA12A antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 75 kDa
      Observed band size: 75 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
  • Uniprot No.：
    O43301
  • 基因名：
    HSPA12A
  • 别名：
    FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HSPA12A Antibody (CSB-PA010817LA01HU)，的标记方式是Non-conjugated。对于HSPA12A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010817LB01HU HSPA12A Antibody, HRP conjugated ELISA
    FITC CSB-PA010817LC01HU HSPA12A Antibody, FITC conjugated
    Biotin CSB-PA010817LD01HU HSPA12A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
  • 基因功能参考文献：
    1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
    2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
    3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Heat shock protein 70 family
  • 组织特异性：
    Widely expressed with highest levels in brain, kidney and muscle.
  • 数据库链接：

    HGNC: 19022

    OMIM: 610701

    KEGG: hsa:259217

    STRING: 9606.ENSP00000358211

    UniGene: Hs.648448