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HSD17B14 Antibody

  • 货号：
    CSB-PA010771GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BPX1
  • 基因名：
    HSD17B14
  • 别名：
    HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HSD17B14
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
  • 基因功能参考文献：
    1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
    2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 组织特异性：
    Highly expressed in brain, placenta, liver and kidney.
  • 数据库链接：

    HGNC: 23238

    OMIM: 612832

    KEGG: hsa:51171

    STRING: 9606.ENSP00000263278

    UniGene: Hs.18788