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HS1BP3 Antibody

  • 货号：
    CSB-PA010745GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q53T59
  • 基因名：
    HS1BP3
  • 别名：
    ETM2 antibody; FLJ14249 antibody; H1BP3_HUMAN antibody; HCLS1 binding protein 3 antibody; HCLS1-binding protein 3 antibody; HS1 binding protein 3 antibody; HS1 BP3 antibody; HS1-binding protein 3 antibody; Hs1bp3 antibody; HSP1BP-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HS1BP3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be a modulator of IL-2 signaling.
  • 基因功能参考文献：
    1. HS1BP3 is localized to ATG16L1- and ATG9-positive autophagosome precursors and we show that HS1BP3 binds phosphatidic acid (PA) through its PX domain. Furthermore, we find the total PA content of cells to be significantly upregulated in the absence of HS1BP3. PMID: 28004827
    2. Results suggest that HS1BP3 regulates apoptosis via HS1 and stimulates AP-1-mediated transcription. PMID: 21699750
    3. The 828C-->G mutation causes a substitution of a glycine for an alanine residue in the HS1-BP3 protein. It was found in 2 unrelated patients with familial essential tremor. PMID: 15699368
    4. HS1PB3 protein is mutated in essential tremor combined with Parkinson disease. PMID: 16116142
    5. Results do not support a role for these DRD3 and HS1BP3 variants in PD. PMID: 19524641

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  • 数据库链接：

    HGNC: 24979

    OMIM: 609359

    KEGG: hsa:64342

    STRING: 9606.ENSP00000305193

    UniGene: Hs.531785