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  4. HOXC4 Antibody

HOXC4 Antibody

  • 中文名称：
    HOXC4兔多克隆抗体
  • 货号：
    CSB-PA010675GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P09017
  • 基因名：
    HOXC4
  • 别名：
    CP 19 antibody; CP19 antibody; Homeo box 3E antibody; Homeo box C4 antibody; Homeo box protein HoxC4 antibody; Homeobox 3E antibody; Homeobox C4 antibody; Homeobox protein CP19 antibody; Homeobox protein Hox C4 antibody; Homeobox protein Hox-3E antibody; Homeobox protein Hox-C4 antibody; Homeobox protein HoxC4 antibody; Homeobox3E antibody; HomeoboxC4 antibody; HOX 3 antibody; Hox 3E antibody; HOX C4 antibody; HOX3 antibody; Hox3E antibody; HOXC 4 antibody; Hoxc4 antibody; HXC4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HOXC4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能参考文献：
    1. HOXC4 homeoprotein expands human hematopoietic immature cells by 3 to 6 times ex vivo and significantly improves the level of in vivo engraftment. PMID: 22298821
    2. Human cytomegalovirus downregulates while all-trans retinoic acid upregulates expression of hoxc4 and hoxc6 in lymphocytic progenitor cells. PMID: 19236766
    3. Esr1 bind to and activate the HOXC4 promoter to potentiate HoxC4-mediated AID induction, immunoglobulin class switch and somatic hypermutation. PMID: 20855884
    4. Selective inhibition of class switching to IgG and IgE by recruitment of this and Oct-1 proteins and Ku70/Ku86 to newly identified ATTT cis-elements. PMID: 12672812
    5. The hs1,2mediated enhancement of V(H) and C(H) promoter-driven transcription as induced by HoxC4 and Oct-1/Oct-2 suggests an important role of these homeodomain proteins in the overall regulation of the IgH locus expression. PMID: 15252056
    6. The HOXC4 expression was clearly detected in all inv(7) positive patients. PMID: 15674412
    7. HoxC4 directly activates the Aicda promoter PMID: 19363484

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Antp homeobox family, Deformed subfamily
  • 数据库链接：

    HGNC: 5126

    OMIM: 142974

    KEGG: hsa:3221

    STRING: 9606.ENSP00000305973

    UniGene: Hs.549040