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HOXA6 Antibody

  • 货号：
    CSB-PA010656EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: HOXA6 antibody at 2µg/ml + Mouse heart tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 27 kDa
      Observed band size: 27 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA010656EA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HOXA6 Polyclonal antibody
  • Uniprot No.：
    P31267
  • 基因名：
    HOXA6
  • 别名：
    Homeo box 1B antibody; Homeo box A6 antibody; Homeobox 1B antibody; Homeobox A6 antibody; Homeobox protein Hox A6 antibody; Homeobox protein Hox-1B antibody; Homeobox protein Hox-A6 antibody; Homeobox protein HoxA6 antibody; HOX 1 antibody; Hox 1B antibody; HOX1 antibody; HOX1.2 antibody; Hox1B antibody; HOXA6 antibody; HX A6 antibody; HXA6 antibody; HXA6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Homeobox protein Hox-A6 protein (1-233AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HOXA6 Antibody (CSB-PA010656EA01HU)，的标记方式是Non-conjugated。对于HOXA6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010656EB01HU HOXA6 Antibody, HRP conjugated ELISA
    FITC CSB-PA010656EC01HU HOXA6 Antibody, FITC conjugated
    Biotin CSB-PA010656ED01HU HOXA6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能参考文献：
    1. Results demonstrated thatHOXA6 is up-regulated in colorectal cancer (CRC) and promoted cell proliferation, migration and invasion, but inhibited apoptosis, whereas the downregulated expression of HOXA6 produced the opposite effects. HOXA6 regulated apoptosis through the Bcl-2 signaling pathway, and regulated migration and invasion through the EMT process. PMID: 29620285
    2. HOXA6 is a signature gene involved in cell growth and sensitivity to chemotherapy in acute myeloid leukemia cells. PMID: 23539541
    3. Data indicate that genes with hypermethylated CpG islands in malignant meningiomas, such as HOXA6 and HOXA9, tend to coincide with the binding sites of polycomb repressive complexes (PRC) in early developmental stage. PMID: 23349797
    4. Enforced overexpression of HOXA6 or HOXA9 in FDCP-Mix resulted in increased proliferation and colony formation but had negligible effect on differentiation in early multipotential and later committed precursor cells PMID: 19157684
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Antp homeobox family
  • 数据库链接：

    HGNC: 5107

    OMIM: 142951

    KEGG: hsa:3203

    STRING: 9606.ENSP00000222728

    UniGene: Hs.679517