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HNRNPAB Antibody

  • 货号：
    CSB-PA010604LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate
      All lanes: HNRNPAB antibody at 2.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37, 36, 31 kDa
      Observed band size: 37, 36 kDa
    • IHC image of CSB-PA010604LA01HU diluted at 1:500 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA010604LA01HU diluted at 1:500 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA010604LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HNRNPAB Polyclonal antibody
  • Uniprot No.：
    Q99729
  • 基因名：
    HNRNPAB
  • 别名：
    ABBP 1 antibody; ABBP-1 antibody; ABBP1 antibody; Apobec 1 binding protein 1 antibody; APOBEC1 binding protein 1 antibody; APOBEC1-binding protein 1 antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1- protein 1 antibody; FLJ40338 antibody; Heterogeneous nuclear ribonucleoprotein A/B antibody; hnRNP A/B antibody; hnRNP type A/B protein antibody; HNRNPAB antibody; HNRPAB antibody; ROAA_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Heterogeneous nuclear ribonucleoprotein A/B protein (1-68AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HNRNPAB Antibody (CSB-PA010604LA01HU)，的标记方式是Non-conjugated。对于HNRNPAB Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010604LB01HU HNRNPAB Antibody, HRP conjugated ELISA
    FITC CSB-PA010604LC01HU HNRNPAB Antibody, FITC conjugated
    Biotin CSB-PA010604LD01HU HNRNPAB Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
  • 基因功能参考文献：
    1. Findings define HNRNPAB as an activator of EMT and metastasis in HCC that predicts poor clinical outcomes. PMID: 24638979
    2. physical association of p63alpha and ABBP1 led to a specific shift of FGFR-2 alternative splicing toward the K-SAM isoform essential for epithelial differentiation PMID: 12692135
  • 亚细胞定位：
    Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 5034

    OMIM: 602688

    KEGG: hsa:3182

    STRING: 9606.ENSP00000351108

    UniGene: Hs.591731