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  4. HMG20A Antibody

HMG20A Antibody

  • 中文名称：
    HMG20A兔多克隆抗体
  • 货号：
    CSB-PA010541GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NP66
  • 基因名：
    HMG20A
  • 别名：
    FLJ10739 antibody; High mobility group 20A antibody; High mobility group protein 20A antibody; HM20A_HUMAN antibody; HMG box containing protein 20A antibody; HMG box domain containing 1 antibody; HMG box-containing protein 20A antibody; HMG domain protein HMGX1 antibody; HMG domain-containing protein 1 antibody; HMG domain-containing protein HMGX1 antibody; hmg20a antibody; HMGX1 antibody; HMGXB1 antibody; Hypothetical protein FLJ10739 antibody; iBRAF antibody; Inhibitor of BRAF35 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HMG20A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
  • 基因功能参考文献：
    1. HMG20A together with LSD1 are required for SNAI1-dependent repression of epithelial genes. PMID: 25639869
    2. ectopic expression of BRAP2 inhibits nuclear localization of HMG20A and NuMA1, and prevents nuclear envelope accumulation of SYNE2. PMID: 23707952
    3. HMG20A/iBRAF forms heterodimers with HMG20B/BRAF35. Heterodimerization impairs HMG20B/BRAF35 sumoylation and interaction with the LSD1-CoREST complex. PMID: 22570500
    4. we report associations with the LAMA1 and HMG20A (not previously associated at genome-wide significance in Europeans) gene regions with type 2 diabetes risk PMID: 22693455
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 5001

    OMIM: 605534

    KEGG: hsa:10363

    STRING: 9606.ENSP00000336856

    UniGene: Hs.69594