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HERC4 Antibody

  • 货号：
    CSB-PA010302GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q5GLZ8
  • 基因名：
  • 别名：
    DKFZP564G092 antibody; HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody; HECT domain and RCC1 like domain containing protein 4 antibody; HECT domain and RCC1-like domain-containing protein 4 antibody; Hect domain and RLD 4 antibody; HERC 4 antibody; HERC4 antibody; HERC4_HUMAN antibody; KIAA1593 antibody; Probable E3 ubiquitin protein ligase HERC4 antibody; Probable E3 ubiquitin-protein ligase HERC4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HERC4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
  • 基因功能参考文献：
    1. HERC4 has an effect on the occurrence and development of hepatoma carcinoma PMID: 28430527
    2. High HERC4 expression is associated with lung cancer. PMID: 25684480
    3. HERC4 ancestor emerged in nematodes and that the family expanded throughout evolution. The mRNA expression pattern of the HERC4 was found to be diverse in selected tissues and cells PMID: 15676274
  • 亚细胞定位：
    Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution.
  • 组织特异性：
    Expressed in brain and testis and detected in heart and placenta.
  • 数据库链接：

    HGNC: 24521

    OMIM: 609248

    KEGG: hsa:26091

    STRING: 9606.ENSP00000378624

    UniGene: Hs.51891