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HELZ2 Antibody

  • 货号：
    CSB-PA070081
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9BYK8
  • 基因名：
    HELZ2
  • 别名：
    ATP-dependent helicase PRIC285 antibody; KIAA1769 antibody; PDIP1 antibody; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein antibody; PPAR-alpha-interacting complex protein 285 antibody; PPAR-gamma DBD-interacting protein 1 antibody; PPAR-gamma DNA-binding domain-interacting protein 1 antibody; PR285_HUMAN antibody; PRIC285 antibody; PRPF8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PRIC285.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.
  • 基因功能参考文献：
    1. Thrap3 could play indispensable roles in terminal differentiation of adipocytes by enhancing PPARgamma-mediated gene activation cooperatively with Helz2. PMID: 23525231
    2. Genetic polymorphisms in PRIC285 gene is associated with autoimmune disease. PMID: 22446964
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    DNA2/NAM7 helicase family
  • 组织特异性：
    Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta.
  • 数据库链接：

    HGNC: 30021

    OMIM: 611265

    KEGG: hsa:85441

    STRING: 9606.ENSP00000417401

    UniGene: Hs.517180