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HAUS8 Antibody

  • 货号：
    CSB-PA863116ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: HAUS8 antibody at 2.35 μg/ml
      Lane 1: Mouse kidney tissue
      Lane 2: Mouse brain tissue
      Lane 3: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 45, 39 kDa
      Observed band size: 45, 50, 28 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA863116ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA863116ESR1HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA863116ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HAUS8 Polyclonal antibody
  • Uniprot No.：
    Q9BT25
  • 基因名：
    HAUS8
  • 别名：
    DGT4 antibody; HAUS augmin like complex subunit 8 antibody; HAUS augmin-like complex subunit 8 antibody; HAUS8 antibody; HAUS8_HUMAN antibody; Hec1 interacting and centrosome associated 1 antibody; HEC1/NDC80 interacting centrosome associated protein 1 antibody; HEC1/NDC80-interacting centrosome-associated protein 1 antibody; HICE 1 antibody; HICE1 antibody; MGC20533 antibody; NY SAR 48 antibody; NY-SAR-48 antibody; Sarcoma antigen NY SAR 48 antibody; Sarcoma antigen NY-SAR-48 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human HAUS augmin-like complex subunit 8 protein (166-410AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
  • 基因功能参考文献：
    1. Aurora-A modulates the microtubule binding activity of Hice1 in a spatiotemporal manner for proper bipolar spindle assembly. PMID: 21705324
    2. Results suggest that Hec1, through cooperation with Hice1, contributes to centrosome-directed microtubule growth to facilitate establishing a proper mitotic spindle. PMID: 19776357
    3. Hice1 is a novel microtubule-associated protein important for maintaining spindle integrity and chromosomal stability, in part by virtue of its ability to bind, bundle, and stabilize microtubules. PMID: 18362163
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    HAUS8 family
  • 数据库链接：

    HGNC: 30532

    OMIM: 613434

    KEGG: hsa:93323

    STRING: 9606.ENSP00000253669

    UniGene: Hs.404088