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GSTM4 Antibody

  • 货号：
    CSB-PA009984ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: GSTM4 antibody at 10μg/ml
      Lane 1: Rat lung tissue
      Lane 2: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 26, 23, 19 kDa
      Observed band size: 26 kDa
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA009984ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA009984ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GSTM4 Polyclonal antibody
  • Uniprot No.：
    Q03013
  • 基因名：
    GSTM4
  • 别名：
    Glutathione S transferase M4 antibody; Glutathione S transferase Mu 4 antibody; Glutathione S-transferase Mu 4 antibody; GST class mu 4 antibody; GST class-mu 4 antibody; GST-Mu2 antibody; GSTM4 4 antibody; GSTM4 antibody; GSTM4-4 antibody; GSTM4_HUMAN antibody; GTM4 antibody; GTS Mu2 antibody; MGC131945 antibody; MGC9247 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Glutathione S-transferase Mu 4 protein (1-218AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:200-1:1000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions.
  • 基因功能参考文献：
    1. We observed suggestive associations between survival and GSTT1 copy number and GSTA5, GSTM4, and ABCC4 single nucleotide polymorphisms PMID: 20200426
    2. A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. PMID: 12140136
    3. a novel splice variant of GSTM4 that resulted from tandem skipping of exons 4 and 5 is identified. PMID: 16854533
    4. GSTM4 (glutathione S-transferase mu 4) haplotype 1101000 may be an important determinant for lung function growth PMID: 19151192
    5. GSTM4 contributes to the cancerous behavior of Ewing's sarcoma. PMID: 19718047

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    GST superfamily, Mu family
  • 组织特异性：
    Expressed in a wide variety of tissues.
  • 数据库链接：

    HGNC: 4636

    OMIM: 138333

    KEGG: hsa:2948

    STRING: 9606.ENSP00000358851

    UniGene: Hs.348387