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GPR75 Antibody

  • 货号：
    CSB-PA009829LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: GPR75 antibody at 8µg/ml + HT29 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 59 kDa
      Observed band size: 59 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA009829LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA009829LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunofluorescent analysis of A549 cells using CSB-PA009829LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    Initially, a rabbit was inoculated with recombinant human GPR75 protein (372-540aa) to generate the GPR75 polyclonal antibody. The resulting antibodies were extracted from the rabbit serum and then purified using protein G affinity chromatography. The purity level of the GPR75 polyclonal antibody was measured to exceed 95%, indicating minimal impurities.

    This GPR75 polyclonal antibody can recognize and bind to the GPR75 protein of human origin. Moreover, it has successfully validated its effectiveness in a range of experimental settings, including ELISA, WB, IHC, and IF, enabling the detection of levels, determination of presence and size, and analysis of the distribution of GPR75 protein.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GPR75 Polyclonal antibody
  • Uniprot No.：
    O95800
  • 基因名：
  • 别名：
    G protein coupled receptor 75 antibody; GPR chr2 antibody; Gpr75 antibody; GPR75_HUMAN antibody; GPRchr2 antibody; OTTHUMP00000159608 antibody; Probable G protein coupled receptor 75 antibody; Probable G-protein coupled receptor 75 antibody; WI 31133 antibody; WI31133 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Probable G-protein coupled receptor 75 protein (372-540AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GPR75 Antibody (CSB-PA009829LA01HU)，的标记方式是Non-conjugated。对于GPR75 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA009829LB01HU GPR75 Antibody, HRP conjugated ELISA
    FITC CSB-PA009829LC01HU GPR75 Antibody, FITC conjugated
    Biotin CSB-PA009829LD01HU GPR75 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cel
  • 数据库链接：

    HGNC: 4526

    OMIM: 606704

    KEGG: hsa:10936

    STRING: 9606.ENSP00000378195

    UniGene: Hs.40763