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  4. GPR133 Antibody

GPR133 Antibody

  • 货号：
    CSB-PA008902
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q6QNK2
  • 基因名：
  • 别名：
    DKFZp434B1272 antibody; FLJ16770 antibody; G protein coupled receptor 133 antibody; G protein coupled receptor PGR25 antibody; G-protein coupled receptor PGR25 antibody; GP133_HUMAN antibody; Gpr133 antibody; MGC138512 antibody; MGC138514 antibody; PGR25 antibody; Probable G-protein coupled receptor 133 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human GPR133.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

平均分:
5.0分 - 1 个评价

实验应用：WB

样品信息：细胞裂解液

稀释比：1:1000

产品评价： 我使用CSB-PA008902抗体进行细胞中GPR133蛋白表达的WB检测，因为是膜蛋白所以用的37℃，30min变性蛋白。上样量为15ug总蛋白，条带很清晰，结果还算不错。

By 刘老师

靶点详情

  • 功能：
    Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
  • 基因功能参考文献：
    1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID: 27516204
    2. Cell adhesion receptor GPR133 couples to Gs protein PMID: 22025619
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID: 20031603
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20031603
    6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19729412

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 组织特异性：
    Up-regulated in CD133(+) cell population of glioblastoma.
  • 数据库链接：

    HGNC: 19893

    OMIM: 613639

    KEGG: hsa:283383

    STRING: 9606.ENSP00000261654

    UniGene: Hs.719239