Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. GPR114 Antibody

GPR114 Antibody

  • 货号：
    CSB-PA008214
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using GPR114 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8IZF4
  • 基因名：
  • 别名：
    ADGRG5; GPR114; PGR27; UNQ2524/PRO6017; Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; G-protein coupled receptor PGR27
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human GPR114.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking).
  • 基因功能参考文献：
    1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20600896
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 组织特异性：
    Expressed in immune cells. Primarily found in granulocytes. Found in eosinophils.
  • 数据库链接：

    HGNC: 19010

    OMIM: 616965

    KEGG: hsa:221188

    STRING: 9606.ENSP00000290823

    UniGene: Hs.187884