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GOLPH3L Antibody

  • 货号：
    CSB-PA009669LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA009669LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA009669LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GOLPH3L Polyclonal antibody
  • Uniprot No.：
    Q9H4A5
  • 基因名：
    GOLPH3L
  • 别名：
    GLP3L_HUMAN antibody; Golgi phosphoprotein 3-like antibody; golph3l antibody; GPP34-related protein antibody; GPP34R antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Golgi phosphoprotein 3-like protein (6-285AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GOLPH3L Antibody (CSB-PA009669LA01HU)，的标记方式是Non-conjugated。对于GOLPH3L Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA009669LB01HU GOLPH3L Antibody, HRP conjugated ELISA
    FITC CSB-PA009669LC01HU GOLPH3L Antibody, FITC conjugated
    Biotin CSB-PA009669LD01HU GOLPH3L Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
  • 基因功能参考文献：
    1. GOLPH3L was markedly upregulated in ovarian cancer cells and clinical ovarian cancer samples, and a positive correlation was evident between GOLPH3L expression and the recurrence-free survival of ovarian cancer patients. PMID: 28978336
    2. GOLPH3L differs critically from GOLPH3 in that it is largely unable to bind to MYO18A; data demonstrate that despite their similarities, unexpectedly, GOLPH3L antagonizes GOLPH3/MYO18A at the Golgi PMID: 23345592
  • 亚细胞定位：
    Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes.
  • 蛋白家族：
    GOLPH3/VPS74 family
  • 数据库链接：

    HGNC: 24882

    OMIM: 612208

    KEGG: hsa:55204

    STRING: 9606.ENSP00000271732

    UniGene: Hs.203699