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GLIPR2 Antibody

  • 货号：
    CSB-PA880974LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA880974LA01HU diluted at 1:600 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GLIPR2 Polyclonal antibody
  • Uniprot No.：
    Q9H4G4
  • 基因名：
    GLIPR2
  • 别名：
    5730414A08Rik antibody; C77180 antibody; C9orf19 antibody; GAPR 1 antibody; GAPR-1 antibody; GAPR1_HUMAN antibody; GLI pathogenesis related 2 antibody; Glioma pathogenesis related protein 2 antibody; Glioma pathogenesis-related protein 2 antibody; GliPR 2 antibody; GLIPR2 antibody; Golgi associated plant pathogenesis related protein 1 antibody; Golgi associated PR 1 protein antibody; Golgi-associated plant pathogenesis-related protein 1 antibody; Golgi-associated PR-1 protein antibody; OTTMUSP00000007558 antibody; RP11-421H8.5 antibody; RP23-209M8.2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Golgi-associated plant pathogenesis-related protein 1 protein (2-85AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GLIPR2 Antibody (CSB-PA880974LA01HU)，的标记方式是Non-conjugated。对于GLIPR2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA880974LB01HU GLIPR2 Antibody, HRP conjugated ELISA
    FITC CSB-PA880974LC01HU GLIPR2 Antibody, FITC conjugated
    Biotin CSB-PA880974LD01HU GLIPR2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. PMID: 28876241
    2. This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. PMID: 26678074
    3. Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. PMID: 24204846
    4. GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway PMID: 23516513
    5. the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function PMID: 22560898

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  • 亚细胞定位：
    Golgi apparatus membrane; Lipid-anchor. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.
  • 蛋白家族：
    CRISP family
  • 组织特异性：
    Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney.
  • 数据库链接：

    HGNC: 18007

    OMIM: 607141

    KEGG: hsa:152007

    STRING: 9606.ENSP00000367196

    UniGene: Hs.493819