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GDPD2 Antibody

  • 货号：
    CSB-PA864028LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: GDPD2 antibody at 1.5µg/ml + A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 62, 53, 67 kDa
      Observed band size: 62 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA864028LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA864028LA01HU at dilution of 1:100
    • Immunofluorescent analysis of U251 cells using CSB-PA864028LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GDPD2 Polyclonal antibody
  • Uniprot No.：
    Q9HCC8
  • 基因名：
    GDPD2
  • 别名：
    GDPD2; GDE3; OBDPF; UNQ1935/PRO4418; Glycerophosphoinositol inositolphosphodiesterase GDPD2; Glycerophosphodiester phosphodiesterase 3; Glycerophosphodiester phosphodiesterase domain-containing protein 2; Osteoblast differentiation promoting factor
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Glycerophosphoinositol inositolphosphodiesterase GDPD2 protein (210-490AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GDPD2 Antibody (CSB-PA864028LA01HU)，的标记方式是Non-conjugated。对于GDPD2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA864028LB01HU GDPD2 Antibody, HRP conjugated ELISA
    FITC CSB-PA864028LC01HU GDPD2 Antibody, FITC conjugated
    Biotin CSB-PA864028LD01HU GDPD2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton.
  • 基因功能参考文献：
    1. The results establish GDE3 as a negative regulator of the uPAR signaling network and, furthermore, highlight GPI-anchor hydrolysis as a cell-intrinsic mechanism to alter cell behavior. PMID: 28849762
    2. GDE3 is a novel seven-transmembrane protein with a GP-PDE-like extracellular motif expressed during osteoblast differentiation that accelerates the program of osteoblast differentiation and is involved in morphological change of cells PMID: 12933806
    3. GDE3 substrate GroPIns is a candidate mediator for osteoblast proliferation PMID: 19596859
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Glycerophosphoryl diester phosphodiesterase family
  • 数据库链接：

    HGNC: 25974

    OMIM: 300940

    KEGG: hsa:54857

    UniGene: Hs.438712