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GCFC2 Antibody

  • 货号：
    CSB-PA050220
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P16383
  • 基因名：
    GCFC2
  • 别名：
    GCFC2 antibody; C2orf3 antibody; GCF antibody; TCF9GC-rich sequence DNA-binding factor 2 antibody; GC-rich sequence DNA-binding factor antibody; Transcription factor 9 antibody; TCF-9 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human TCF-9.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised introns.
  • 基因功能参考文献：
    1. s propose the GCF regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5. PMID: 26915404
    2. C2ORF3 protein is required for pre-mRNA splicing through its presumable role in efficient intron turnover PMID: 24304693
    3. Study refined the 2p12 candidate region in two populations and report evidence supporting MRPL19 and C2ORF3 as candidate susceptibility genes for dyslexia. PMID: 17309879
  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus, nucleolus.
  • 蛋白家族：
    GCF family
  • 组织特异性：
    Widely expressed in tissues and cell lines.
  • 数据库链接：

    HGNC: 1317

    OMIM: 189901

    KEGG: hsa:6936

    STRING: 9606.ENSP00000318690

    UniGene: Hs.303808