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GATAD2A Antibody

  • 货号：
    CSB-PA803156LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, 293 whole cell lysate, HL60 whole cell lysate, MCF-7 whole cell lysate, Rat stomach tissue
      All lanes: GATAD2A antibody at 2.9μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 69, 66 kDa
      Observed band size: 69 kDa
    • IHC image of CSB-PA803156LA01HU diluted at 1:800 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA803156LA01HU diluted at 1:800 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GATAD2A Polyclonal antibody
  • Uniprot No.：
    Q86YP4
  • 基因名：
    GATAD2A
  • 别名：
    FLJ20085 antibody; FLJ21017 antibody; GATA zinc finger domain containing 2A antibody; GATA zinc finger domain containing protein 2A antibody; GATA zinc finger domain-containing protein 2A antibody; GATAD2A antibody; Hp66 alpha antibody; Hp66alpha antibody; OTTHUMP00000201911 antibody; OTTHUMP00000201912 antibody; P66 alpha antibody; P66A_HUMAN antibody; p66alpha antibody; Transcriptional repressor p66 alpha antibody; Transcriptional repressor p66-alpha antibody; Transcriptional repressor p66alpha antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Transcriptional repressor p66-alpha protein (170-241AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GATAD2A Antibody (CSB-PA803156LA01HU)，的标记方式是Non-conjugated。对于GATAD2A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA803156LB01HU GATAD2A Antibody, HRP conjugated ELISA
    FITC CSB-PA803156LC01HU GATAD2A Antibody, FITC conjugated
    Biotin CSB-PA803156LD01HU GATAD2A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B.
  • 基因功能参考文献：
    1. The MYND domain of ZMYND8 directly interacts with PPPLPhi motifs in the NuRD subunit GATAD2A. PMID: 27732854
    2. Results showed that suppression of GATAD2A attenuated thyroid cancer cell proliferation and colony formation and promoted apoptosis suggesting it as an essential factor in thyroid cancer cell pathogenesis. PMID: 28260108
  • 亚细胞定位：
    Nucleus speckle.
  • 组织特异性：
    Ubiquitous, both in fetal and adult tissues.
  • 数据库链接：

    HGNC: 29989

    OMIM: 614997

    KEGG: hsa:54815

    STRING: 9606.ENSP00000351552

    UniGene: Hs.118964