Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. GAREM1 Antibody

GAREM1 Antibody

  • 货号：
    CSB-PA863993LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA863993LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA863993LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GAREM1 Polyclonal antibody
  • Uniprot No.：
    Q9H706
  • 基因名：
    GAREM1
  • 别名：
    GAREM1 antibody; C18orf11 antibody; FAM59A antibody; GAREM antibody; GRB2-associated and regulator of MAPK protein 1 antibody; GRB2-associated and regulator of MAPK1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human GRB2-associated and regulator of MAPK protein (12-320AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GAREM1 Antibody (CSB-PA863993LA01HU)，的标记方式是Non-conjugated。对于GAREM1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863993LB01HU GAREM1 Antibody, HRP conjugated ELISA
    FITC CSB-PA863993LC01HU GAREM1 Antibody, FITC conjugated
    Biotin CSB-PA863993LD01HU GAREM1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.
  • 基因功能参考文献：
    1. We have provided evidence that GAREM1 is involved in the PR interval of ECGs. These findings increase our understanding of the regulatory signals of heart rhythm through intracardiac ganglia of the autonomic nervous system and can be used to guide the development of a therapeutic target for heart conditions, such as atrial fibrillation. PMID: 29273731
    2. suggest that the interplay between 14-3-3, SAM domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells. PMID: 26164232
    3. Data indicate that a subtype of GAREM, GAREM2, is specifically expressed in the mouse, rat, and human brain. PMID: 24003223
    4. Extracellular signal-regulated kinase activation in response to epidermal growth factor stimulation is regulated by the expression of GAREM in COS-7 and HeLa cells. PMID: 19509291
  • 蛋白家族：
    GAREM family
  • 组织特异性：
    Isoform 1 is ubiquitously expressed.
  • 数据库链接：

    HGNC: 26136

    KEGG: hsa:64762

    UniGene: Hs.444314