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GALNT17 Antibody

  • 货号：
    CSB-PA743592LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA743592LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA743592LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GALNT17 Polyclonal antibody
  • Uniprot No.：
    Q6IS24
  • 基因名：
    GALNT17
  • 别名：
    GALNT17 antibody; WBSCR17Polypeptide N-acetylgalactosaminyltransferase 17 antibody; EC 2.4.1.41 antibody; Polypeptide GalNAc transferase-like protein 3 antibody; GalNAc-T-like protein 3 antibody; pp-GaNTase-like protein 3 antibody; Protein-UDP acetylgalactosaminyltransferase-like protein 3 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3 antibody; Williams-Beuren syndrome chromosomal region 17 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 17 protein (101-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GALNT17 Antibody (CSB-PA743592LA01HU)，的标记方式是Non-conjugated。对于GALNT17 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA743592LB01HU GALNT17 Antibody, HRP conjugated ELISA
    FITC CSB-PA743592LC01HU GALNT17 Antibody, FITC conjugated
    Biotin CSB-PA743592LD01HU GALNT17 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
  • 基因功能参考文献：
    1. GWA study identified maternal genetic effects not previously identified in ASD at a locus in WBSCR17. PMID: 27876814
    2. a subset of O-glycosylation produced by WBSCR17 controls dynamic membrane trafficking, probably between the cell surface and the late endosomes through macropinocytosis PMID: 22787146
  • 相关疾病：
    WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 组织特异性：
    Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen.
  • 数据库链接：

    HGNC: 16347

    OMIM: 615137

    KEGG: hsa:64409

    STRING: 9606.ENSP00000329654

    UniGene: Hs.488591