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FRYL Antibody

  • 货号：
    CSB-PA009007LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA009007LA01HU diluted at 1:600 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of U251 cells with CSB-PA009007LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FRYL Polyclonal antibody
  • Uniprot No.：
    O94915
  • 基因名：
    FRYL
  • 别名：
    2010313D22Rik antibody; 2310004H21Rik antibody; 2510002A14Rik antibody; 9030227G01Rik antibody; AF4P12 antibody; AI930088 antibody; ALL fused gene from chromosome 4p12 antibody; ALL1-fused gene from chromosome 4p12 protein antibody; DKFZp686E205 antibody; FLJ161772 antibody; FRY like antibody; FRYL antibody; FRYL_HUMAN antibody; Furry homolog like (Drosophila) antibody; Furry homolog like antibody; Furry like antibody; KIAA0826 antibody; mKIAA0826 antibody; Protein furry homolog-like antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein furry homolog-like protein (42-739AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FRYL Antibody (CSB-PA009007LA01HU)，的标记方式是Non-conjugated。对于FRYL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA009007LB01HU FRYL Antibody, HRP conjugated ELISA
    FITC CSB-PA009007LC01HU FRYL Antibody, FITC conjugated
    Biotin CSB-PA009007LD01HU FRYL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. May function as a transcriptional activator.
  • 基因功能参考文献：
    1. Thus, t(4;11)(p12;q23) with MLL and FRYL involvement represents a new recurring 11q23 translocation, to date seen only in therapy-related acute leukemias. PMID: 17854671
  • 相关疾病：
    A chromosomal aberration involving FRYL is found in treatment-related acute lymphoblastic leukemia (ALL). Translocation t(4;11)(p12;q23) that forms a KMT2A/MLL1-FRYL fusion protein.
  • 蛋白家族：
    Furry protein family
  • 组织特异性：
    Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin.
  • 数据库链接：

    HGNC: 29127

    KEGG: hsa:285527

    STRING: 9606.ENSP00000351113

    UniGene: Hs.595553