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FMRFa Antibody

  • 中文名称：
    FMRFa兔多克隆抗体
  • 货号：
    CSB-PA016032XA01DLU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • Uniprot No.：
    P10552
  • 基因名：
    FMRFa
  • 别名：
    FMRFamide-related peptides [Cleaved into: FMRFamide A; Corticotropin-releasing factor-like; AAMDRY-amide; DPKQDFMRF-amide; TPAEDFMRF-amide; SDNFMRF-amide; SPKQDFMRF-amide; PDNFMRF-amide; SAPQDFVRS-amide; MDSNFIRF-amide] FMRFa Fmrf CG2346
  • 反应种属：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Synthetic Peptide (204-208aa)
  • 免疫原种属：
    Drosophila melanogaster (Fruit fly)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Affinity-chromatography
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    In insects, FMRFamide and related peptides have modulatory actions at skeletal neuromuscular junctions, and peptides that are immunologically related to FMRFamide are released into the circulation from neurohemal organs.
  • 基因功能参考文献：
    1. Animals mutant for either FMRFamide or for the FMRFamide receptor (FR) have a reduced recovery sleep in response to heat stress. PMID: 25668617
    2. DPKQDFMRFamide induces contractions via a G-protein coupled FMRFamide receptor in muscle cells but does not appear to act via cAMP, cGMP, CaMKII or arachidonic acid. PMID: 24526728
    3. Klu is expressed specifically in the postmitotic Ap4/FMRFa neuron, promoting its differentiation through the initiation of BMP signaling PMID: 23633512
    4. DPKQDFMRFamide modulates both synaptic function and behavior through coincident detection mediated by FMRF receptor and dromyosuppressin receptor-2. PMID: 21048131
    5. Here, we review FMRFamide-containing peptides encoded by the D. melanogaster FMRFamide gene in order to review the data on the expression, regulation, and activity of these peptides as well as acknowledge endeavors required to elucidate FaRP signaling. PMID: 11814637
    6. Supplying FMRFa in neurosecretory cells partially rescues the wit lethal phenotype. PMID: 14507784
    7. hybridization in situ shows a lack of co-localization of mRNAs for the circadian neuropeptide PDF and FMRFamide in brains of the flies Musca domestica and Drosophila melanogaster PMID: 17426155

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    FARP (FMRFamide related peptide) family
  • 数据库链接：

    KEGG: dme:Dmel_CG2346

    STRING: 7227.FBpp0087471

    UniGene: Dm.7156