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FMO2 Antibody

  • 货号：
    CSB-PA857449ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA857449ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA857449ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FMO2 Polyclonal antibody
  • Uniprot No.：
    Q99518
  • 基因名：
    FMO2
  • 别名：
    2310008D08Rik antibody; 2310042I22Rik antibody; AW107733 antibody; Dimethylaniline monooxygenase [N oxide forming] 2 antibody; Dimethylaniline monooxygenase [N-oxide-forming] 2 antibody; Dimethylaniline oxidase 2 antibody; Flavin containing monooxygenase 2 (non functional) antibody; Flavin containing monooxygenase 2 antibody; FLJ40826 antibody; FMO 1B1 antibody; FMO 2 antibody; FMO antibody; FMO pulmonary antibody; FMO1B1 antibody; FMO2 antibody; FMO2_HUMAN antibody; MGC28212 antibody; OTTMUSP00000028686 antibody; OTTMUSP00000028687 antibody; Pulmonary flavin containing monooxygenase 2 antibody; Pulmonary flavin-containing monooxygenase 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 2 protein (210-470AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole.
  • 基因功能参考文献：
    1. study provides an evidence for the existence of an evolutionary adaptation to an ancient disease based on an ancestral genetic variant acting in a FMO2 haplotypic framework in Ethiopian populations PMID: 28981537
    2. analysis of flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics PMID: 15864117
    3. analysis of how the functional variant flavin-containing monooxygenase 2*1 is at high frequency throughout sub-Saharan Africa PMID: 18794725
    4. Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K. PMID: 19420133
  • 亚细胞定位：
    Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    FMO family
  • 组织特异性：
    Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
  • 数据库链接：

    HGNC: 3770

    OMIM: 603955

    KEGG: hsa:2327

    STRING: 9606.ENSP00000209929

    UniGene: Hs.144912