Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. FBXO8 Antibody

FBXO8 Antibody

  • 中文名称：
    FBXO8兔多克隆抗体
  • 货号：
    CSB-PA008517GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NRD0
  • 基因名：
    FBXO8
  • 别名：
    DC10 antibody; F box only protein 8 antibody; F box protein 8 antibody; F box protein Fbx8 antibody; F box/SEC7 protein FBS antibody; F-box only protein 8 antibody; F-box/SEC7 protein FBS antibody; FBS antibody; FBX8 antibody; FBX8_HUMAN antibody; FBXO 8 antibody; Fbxo8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human FBXO8
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).
  • 基因功能参考文献：
    1. Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC. The preferential down-regulation of FBX8 in HCC patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC progression. PMID: 23826080
    2. FBX8 as a metastasis suppressor that functions through mTOR signaling pathway and has significant prognostic power. PMID: 27916606
    3. FBX8 down-expression was an independent prognostic indicator for glioma patient's survival. PMID: 25550853
    4. FBX8 was markedly down-regulated in gastric cancer tissues. Knocking down FBX8 promoted proliferation and invasion in tumor cell line. Patients with low FBX8 had poor prognosis. PMID: 25801334
    5. FBX8 is a novel c-Myc binding protein and that c-Myc induces cell invasive activity PMID: 20848231

    显示更多

    收起更多

  • 数据库链接：

    HGNC: 13587

    OMIM: 605649

    KEGG: hsa:26269

    STRING: 9606.ENSP00000377280

    UniGene: Hs.76917