Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. FBXO28 Antibody

FBXO28 Antibody

  • 货号：
    CSB-PA889119LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA889119LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA889119LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FBXO28 Polyclonal antibody
  • Uniprot No.：
    Q9NVF7
  • 基因名：
    FBXO28
  • 别名：
    CENP 30 antibody; Centromere protein 30 antibody; F box only protein 28 antibody; F box protein 28 antibody; F-box only protein 28 antibody; Fbx28 antibody; FBX28_HUMAN antibody; FBXO28 antibody; FLJ10766 antibody; KIAA0483 antibody; OTTHUMP00000035597 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human F-box only protein 28 protein (251-368AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FBXO28 Antibody (CSB-PA889119LA01HU)，的标记方式是Non-conjugated。对于FBXO28 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA889119LB01HU FBXO28 Antibody, HRP conjugated ELISA
    FITC CSB-PA889119LC01HU FBXO28 Antibody, FITC conjugated
    Biotin CSB-PA889119LD01HU FBXO28 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • 基因功能参考文献：
    1. It was shown on human primary islets that FBXO28 improves pancreatic beta-cell survival under diabetogenic conditions without affecting insulin secretion. PMID: 29587369
    2. Expression levels of TP53BP2, FBXO28, and FAM53A genes were associated with patient survival specifically in ER-positive, TP53-mutated tumors. PMID: 28179588
    3. Fbxo28 regulates topoisomerase IIalpha decatenation activity and plays an important role in maintaining genomic stability. PMID: 27754753
    4. Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures. PMID: 24357076
    5. Study identified F-box protein, FBXO28 that controls MYC-dependent transcription by non-proteolytic ubiquitylation. Depletion of FBXO28 or overexpression of an F-box mutant unable to support MYC ubiquitylation results in an impairment of MYC-driven transcription, transformation and tumourigenesis. PMID: 23776131

    显示更多

    收起更多

  • 亚细胞定位：
    Chromosome, centromere, kinetochore.
  • 数据库链接：

    HGNC: 29046

    OMIM: 609100

    KEGG: hsa:23219

    STRING: 9606.ENSP00000355827

    UniGene: Hs.64691