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FASTKD1 Antibody

  • 货号：
    CSB-PA002493
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COS7 cells using FASTKD1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q53R41
  • 基因名：
    FASTKD1
  • 别名：
    FAKD1_HUMAN antibody; FAST kinase domain containing protein 1 antibody; FAST kinase domain-containing protein 1 antibody; FAST kinase domains 1 antibody; FASTKD1 antibody; FLJ21901 antibody; KIAA1800 antibody; OTTHUMP00000207008 antibody; OTTHUMP00000207010 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human FASTKD1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
  • 基因功能参考文献：
    1. Disruption of FASTKD1 increases ND3 mRNA level. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone. Each RAP domain of FASTK proteins contains a nuclease fold with a conserved aspartate residue at the putative active site. The RAP domain is essential for the function of the FASTK proteins, while the region upstream determines RNA targeting and protein localization. PMID: 28335001
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    FAST kinase family
  • 组织特异性：
    Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart.
  • 数据库链接：

    HGNC: 26150

    OMIM: 617529

    KEGG: hsa:79675

    UniGene: Hs.529276