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FARP1 Antibody

  • 货号：
    CSB-PA897492LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: A375 whole cell lysate, HEK293 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate
      All lanes: FARP1 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 119, 123, 15 kDa
      Observed band size: 119 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA897492LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA897492LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA897492LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunofluorescent analysis of A549 cells using CSB-PA897492LA01HU at dilution of 1:100 and Cy3-congugated Goat Anti-Rabbit IgG
  • 其他：

产品详情

  • 产品描述：

    The generation of the product CSB-PA897492LA01HU is through immunizing rabbits with the peptide corresponding to amino acids 1-300 of the recombinant human FARP1 protein. The production is a polyclonal antibody and occurs as an unconjugated IgG. It is reactive with human FARP1 protein, which participates in regulating neuronal development through interacting with cell-surface proteins such as class A Plexins and SynCAM 1. Its purity is greater than 95% using protein G purified. And this FARP1 antibody has been validated for use in ELISA, WB, IHC, and IF applications.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FARP1 Polyclonal antibody
  • Uniprot No.：
    Q9Y4F1
  • 基因名：
    FARP1
  • 别名：
    CDEP antibody; Chondrocyte derived ezrin like protein antibody; Chondrocyte-derived ezrin-like protein antibody; FARP1 antibody; FARP1_HUMAN antibody; FERM RhoGEF and pleckstrin domain containing protein 1 antibody; FERM antibody; FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) antibody; FERM; ARHGEF; and pleckstrin domain protein 1 antibody; PH domain-containing family C member 2 antibody; Pleckstrin homology domain-containing family C member 2 antibody; PLEKHC2 antibody; PPP1R75 antibody; protein phosphatase 1; regulatory subunit 75 antibody; RhoGEF and pleckstrin domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 1 protein (1-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FARP1 Antibody (CSB-PA897492LA01HU)，的标记方式是Non-conjugated。对于FARP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897492LB01HU FARP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA897492LC01HU FARP1 Antibody, FITC conjugated
    Biotin CSB-PA897492LD01HU FARP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses.
  • 基因功能参考文献：
    1. We have reported here for the first time a reduced activity of both Rac1 and Cdc42 in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1, ARHGEF1, and ARHGAP36 PMID: 26911374
  • 亚细胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome. Cytoplasm, cytosol. Cell projection, filopodium. Cell projection, dendrite. Cell projection, dendritic spine.
  • 组织特异性：
    Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung.
  • 数据库链接：

    HGNC: 3591

    OMIM: 602654

    KEGG: hsa:10160

    STRING: 9606.ENSP00000322926

    UniGene: Hs.403917