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  4. FAM120A Antibody

FAM120A Antibody

  • 货号：
    CSB-PA008027GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NZB2
  • 基因名：
    FAM120A
  • 别名：
    C9orf10 antibody; Chromosome 9 open reading frame 10 antibody; Constitutive coactivator of PPAR gamma like protein 1 antibody; Constitutive coactivator of PPAR-gamma-like protein 1 antibody; DNA polymerase transactivated protein 5 antibody; DNA polymerase transactivated protein 1 antibody; DNAPTP1 antibody; DNAPTP5 antibody; F120A_HUMAN antibody; FAM120A antibody; Family with sequence similarity 120A antibody; Hypothetical protein LOC23196 antibody; KIAA0183 antibody; LOC23196 antibody; MGC111527 antibody; MGC133257 antibody; OSSA antibody; Oxidative stress-associated Src activator antibody; Protein FAM120A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human FAM120A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
  • 基因功能参考文献：
    1. his study shows that widespread structural brain involvement is not limited to C9+ patients, but also presents in a subgroup of C9- patients with ALS and relates to cognitive deficits. Our neuroimaging findings reveal an intermediate phenotype that may provide insight into the complex relationship between genetic factors and clinical characteristics. PMID: 27756805
    2. Results identify novel SNP in FAM120A on chromosome 9 associated with differences in BMI in childhood which may predispose obesity. PMID: 25953783
    3. Results identified FAM120A in the IL13/IL13Ralpha2 signaling pathway as a key mediator of invasion and liver metastasis in colon cancer. PMID: 25896327
    4. study reports that C9orf10 (designated Ossa for oxidative stress-associated Src activator) is a novel RNA-binding protein that guards cancer cells from oxidative stress-induced apoptosis by activation of Src family kinases PMID: 19015244
  • 亚细胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.
  • 蛋白家族：
    Constitutive coactivator of PPAR-gamma family
  • 组织特异性：
    Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
  • 数据库链接：

    HGNC: 13247

    OMIM: 612265

    KEGG: hsa:23196

    STRING: 9606.ENSP00000277165

    UniGene: Hs.372003