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ERGIC1 Antibody

  • 货号：
    CSB-PA842630LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ERGIC1 antibody at 2µg/ml + HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 33, 23, 18 kDa
      Observed band size: 33 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA842630LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA842630LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ERGIC1 Polyclonal antibody
  • Uniprot No.：
    Q969X5
  • 基因名：
  • 别名：
    ERGIC1; ERGIC32; KIAA1181; HT034; Endoplasmic reticulum-Golgi intermediate compartment protein 1; ER-Golgi intermediate compartment 32 kDa protein; ERGIC-32
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Endoplasmic reticulum-Golgi intermediate compartment protein 1 protein (48-254AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ERGIC1 Antibody (CSB-PA842630LA01HU)，的标记方式是Non-conjugated。对于ERGIC1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842630LB01HU ERGIC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA842630LC01HU ERGIC1 Antibody, FITC conjugated
    Biotin CSB-PA842630LD01HU ERGIC1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Possible role in transport between endoplasmic reticulum and Golgi.
  • 基因功能参考文献：
    1. Homozygous pathogenic variant in the endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 protein (ERGIC1) gene was identified in arthrogryposis multiplex congenita (AMC) neuropathic type. PMID: 28317099
    2. ERGIC1 might play an inhibitory role in the initiation and progression of gastric cancer. PMID: 29549924
    3. Data indicate that abnormal ERGIC1 and DNA-PKcs expression may play an important role in gastric cancer initiation. PMID: 28970727
    4. AIM1, ERGIC1, and TPX2 were shown to be highly expressed especially in prostate cancer tissues, and high mRNA expression of ERGIC1 and TMED3 associated with AR and ERG oncogene expression PMID: 22761906
    5. ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46 PMID: 15308636

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
  • 蛋白家族：
    ERGIC family
  • 数据库链接：

    HGNC: 29205

    KEGG: hsa:57222

    STRING: 9606.ENSP00000377374

    UniGene: Hs.509163