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EPS8L2 Antibody

  • 货号：
    CSB-PA204841
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EPS8L2 Polyclonal antibody
  • Uniprot No.：
    Q9H6S3
  • 基因名：
    EPS8L2
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human ES8L2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells.
  • 基因功能参考文献：
    1. frame-shift variant (c.1014delC; p.Ser339Alafs*15) was identified in EPS8L2, encoding Epidermal growth factor receptor Pathway Substrate 8 L2, a protein of hair cells' stereocilia previously implicated in progressive deafness in the mouse PMID: 26282398
  • 相关疾病：
    Deafness, autosomal recessive, 106 (DFNB106)
  • 亚细胞定位：
    Cytoplasm. Cell projection, stereocilium.
  • 蛋白家族：
    EPS8 family
  • 组织特异性：
    Detected in fibroblasts and placenta.
  • 数据库链接：

    HGNC: 21296

    OMIM: 614988

    KEGG: hsa:64787

    STRING: 9606.ENSP00000320828

    UniGene: Hs.55016