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  4. EPN3 Antibody

EPN3 Antibody

  • 货号：
    CSB-PA030170
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9H201
  • 基因名：
  • 别名：
    EPN 3 antibody; Epn3 antibody; EPN3_HUMAN antibody; EPS 15 interacting protein 3 antibody; EPS-15-interacting protein 3 antibody; Epsin 3 antibody; Epsin-3 antibody; Epsin3 antibody; FLJ20778 antibody; MGC129899 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Epsin 3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. These results suggested that EPN3 enhances the migration and invasion of glioblastoma cells by activating the transcription factors Slug, Twist and ZEB1, but not Snail 1 or ZEB2, to induce EMT in glioma cells; EPN3 involvement in the Notch and WNT/betacatenin signaling pathways may contribute to this process. PMID: 30226603
    2. High expression of epsin (EPN3) was associated with increased risk of late metastasis. PMID: 27926932
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
  • 蛋白家族：
    Epsin family
  • 组织特异性：
    Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
  • 数据库链接：

    HGNC: 18235

    OMIM: 607264

    KEGG: hsa:55040

    STRING: 9606.ENSP00000268933

    UniGene: Hs.670090