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ENPP4 Antibody

  • 货号：
    CSB-PA007682GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y6X5
  • 基因名：
    ENPP4
  • 别名：
    KIAA0879 antibody; 4933413N07Rik antibody; AA986363 antibody; AI195364 antibody; E-NPP 4 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 antibody; ENPP4 antibody; ENPP4_HUMAN antibody; Gm90 antibody; mKIAA0879 antibody; NPP-4 antibody; NPP4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ENPP4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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靶点详情

  • 功能：
    Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
  • 基因功能参考文献：
    1. The combined studies expand our understanding of NPP1 and NPP4 substrate specificity and range and provide a rational mechanism by which polymorphisms in NPP1 confer stroke resistance. PMID: 24338010
    2. NPP4 promotes hemostasis in vivo by augmenting ADP-mediated platelet aggregation at the site of vascular injury. PMID: 22995898
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Nucleotide pyrophosphatase/phosphodiesterase family
  • 组织特异性：
    Expressed on the surface of vascular endothelia.
  • 数据库链接：

    HGNC: 3359

    OMIM: 617000

    KEGG: hsa:22875

    STRING: 9606.ENSP00000318066

    UniGene: Hs.643497