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EMB Antibody

  • 货号：
    CSB-PA754239LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: NIH/3T3 whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue, Rat heart tissue
      All lanes: EMB antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37, 32 kDa
      Observed band size: 70 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA754239LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA754239LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EMB Polyclonal antibody
  • Uniprot No.：
    Q6PCB8
  • 基因名：
    EMB
  • 别名：
    Emb antibody; EMB_HUMAN antibody; Embigin antibody; Embigin homolog (mouse) antibody; embigin homolog antibody; MGC71745 antibody; OTTHUMP00000161812 antibody; OTTHUMP00000221477 antibody; OTTHUMP00000221478 antibody; OTTHUMP00000221479 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Embigin protein (285-327AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，EMB Antibody (CSB-PA754239LA01HU)，的标记方式是Non-conjugated。对于EMB Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA754239LB01HU EMB Antibody, HRP conjugated ELISA
    FITC CSB-PA754239LC01HU EMB Antibody, FITC conjugated
    Biotin CSB-PA754239LD01HU EMB Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
  • 基因功能参考文献：
    1. Study reports elevated expression of Embigin in pancreatic ductal adenocarcinoma and shows its novel functions in regulating cell proliferation, migration, and invasion. PMID: 25773908
    2. embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors PMID: 26090721
    3. Data show that Gp70 (embigin) was negative in all normal, adjacent non-neoplastic and PIN lesions and only a very small percentage of cases. PMID: 21787388
    4. Reports the original cloning of the mouse embigin gene, referred to as gp70, from embryonal carcinoma cells. PMID: 2963822
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
  • 数据库链接：

    HGNC: 30465

    OMIM: 615669

    KEGG: hsa:133418

    STRING: 9606.ENSP00000302289

    UniGene: Hs.561411