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ELMO3 Antibody

  • 货号：
    CSB-PA846590LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA846590LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA846590LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ELMO3 Polyclonal antibody
  • Uniprot No.：
    Q96BJ8
  • 基因名：
    ELMO3
  • 别名：
    CED 12 antibody; Ced 12 homolog 3 antibody; CED12 antibody; ELMO 3 antibody; ELMO3 antibody; ELMO3_HUMAN antibody; Engulfment and cell motility 3 antibody; Engulfment and cell motility protein 3 antibody; FLJ13824 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Engulfment and cell motility protein 3 protein (464-596AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ELMO3 Antibody (CSB-PA846590LA01HU)，的标记方式是Non-conjugated。对于ELMO3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846590LB01HU ELMO3 Antibody, HRP conjugated ELISA
    FITC CSB-PA846590LC01HU ELMO3 Antibody, FITC conjugated
    Biotin CSB-PA846590LD01HU ELMO3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 基因功能参考文献：
    1. the silencing of ELMO3 inhibited cell proliferation, invasion, metastasis, and F-actin polymerization, and induced Gap 1 (G1) phase cell cycle arrest, demonstrating that ELMO3 is involved in the processes of growth, invasion and metastasis of Colorectal Cancer PMID: 27999268
    2. The purpose of this study was to asses ELMO3 expression in postoperatively irradiated head and neck squamous cell carcinoma patients. PMID: 28039609
    3. The over-expression of ELMO3 was a potential diagnostic and prognostic marker for non-small cell lung cancer. PMID: 26191257
    4. The present study reports the first characterization of the ELMO3 promoter and suggests a significant role of CDX2 in the basal transcriptional regulation of the intestine-specific expression of ELMO3, possibly through interaction with SP1. PMID: 20127720
  • 亚细胞定位：
    Cytoplasm.
  • 数据库链接：

    HGNC: 17289

    OMIM: 606422

    KEGG: hsa:79767

    STRING: 9606.ENSP00000377566

    UniGene: Hs.377416