EIF3M Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) EIF3M Polyclonal antibody
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Uniprot No.:Q7L2H7
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基因名:EIF3M
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别名:B5 antibody; B5 receptor antibody; Dendritic cell protein antibody; eIF3m antibody; EIF3M_HUMAN antibody; Eukaryotic translation initiation factor 3 subunit M antibody; Fetal lung protein B5 antibody; FLJ29030 antibody; GA17 antibody; hfl B5 antibody; hFL-B5 antibody; PCI domain containing 1 (herpesvirus entry mediator) antibody; PCI domain-containing protein 1 antibody; PCID1 antibody; TANGO7 antibody
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宿主:Rabbit
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反应种属:Human, Mouse
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免疫原:Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (1-374AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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产品提供形式:Liquid
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应用范围:ELISA, WB, IHC, IP
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推荐稀释比:
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature...显示更多
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基因功能参考文献:
- POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
- eIF3m mediates regulation of tumorigenesis-related genes in human colon cancer PMID: 20838379
- Results demonstrate that B5 plays a major role in the initiation of HSV protein translation and could provide a novel target for strategies to prevent primary and recurrent herpetic disease. PMID: 20676407
- Cloned a previously uncharacterized human gene, designated hfl-B5, and showed that it encodes a type II cell surface membrane protein that can serve as a receptor for entry of HSV. PMID: 15919898
- Concluded that the C terminus of B5 contains a functional region that is important for the B5 receptor to mediate events in HSV entry. PMID: 15919899
- the human Tango7 counterpart, PCID1 (also known as EIF3M), impinged on caspase 9, revealing a new regulatory axis affecting the apoptosome PMID: 19483676
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亚细胞定位:Cytoplasm.
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蛋白家族:EIF-3 subunit M family
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组织特异性:Broadly expressed.
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数据库链接:
HGNC: 24460
OMIM: 609641
KEGG: hsa:10480
STRING: 9606.ENSP00000436049
UniGene: Hs.502244