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  4. EGFL6 Antibody

EGFL6 Antibody

  • 货号：
    CSB-PA138359
  • 规格：
    ￥1100
  • 图片：
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA138359(EGFL6 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q8IUX8
  • 基因名：
    EGFL6
  • 别名：
    EGF like domain multiple 6 antibody; EGF repeat containing protein 6 antibody; EGF-like protein 6 antibody; EGF-like-domain multiple 6 antibody; egfl6 antibody; EGFL6_HUMAN antibody; epidermal growth factor like protein 6 antibody; Epidermal growth factor-like protein 6 antibody; MAEG antibody; MAM and EGF domain containing antibody; MAM and EGF domains containing gene protein antibody; MAM and EGF domains-containing gene protein antibody; W80 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human EGFL6
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.
  • 基因功能参考文献：
    1. In conclusion, our results suggest that plasma level of EGFL6 may be useful to assess disease progression, and especially advanced T status and higher TNM stage in patients with oral squamous cell carcinoma. PMID: 28539817
    2. EGFL6 is an angiocrine and tumor cell factor that promotes tumorigenesis via SHP2-mediated signaling. EGFL6 stimulates ALDH+ ovarian cancer stem cell to migrate and undergo asymmetric division. PMID: 27803106
    3. EGFL6 was overexpressed in benign meningioma tissues and serum. PMID: 23285163
    4. results indicate that human EGFL6 is a paracrine/autocrine growth factor of adipose tissue up-regulated in obesity and potentially involved in the process of adipose tissue expansion and the development of obesity PMID: 20574786
    5. There is an absence of GNAS and EGFL6 mutations in common human cancers. PMID: 18038328

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 蛋白家族：
    Nephronectin family
  • 数据库链接：

    HGNC: 3235

    OMIM: 300239

    KEGG: hsa:25975

    STRING: 9606.ENSP00000369976

    UniGene: Hs.12844